Article
Apoptotic phenotype alters the capacity of tumor necrosis factor-related apoptosis-inducing ligand to induce human vascular endothelial activation.
Journal of vascular research - 1 Jan 2008
Chen Pei-Lin, Easton Alexander
Abstract excerpt
BACKGROUND/AIMS: The ability of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to activate vascular endothelium is unclear. This study investigates the link between endothelial apoptosis and activation in response to TRAIL. METHODS AND RESULTS: Endothelial cell apoptosis was modeled with the immortalized human endothelial cell line EA.hy926, and with primary human umbilical vein endothelial cells...
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