Article
Identification of a novel germline missense mutation of the androgen receptor in African American men with familial prostate cancer.
Asian journal of andrology - 1 May 2010
Hu Si-Yi, Liu Tao, Liu Zhen-Zhen, Ledet Elisa, Velasco-Gonzalez Cruz, Mandal Diptasri M, Koochekpour Shahriar
Abstract excerpt
Race, family history and age are the unequivocally accepted risk factors for prostate cancer (PCa). Androgen receptor (AR)-dependent signaling is an important element in prostate carcinogenesis and its progression to metastatic disease. We examined the possibility of genomic changes in the AR in...
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