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Article

Key interactions in neocarzinostatin, a protein of the immunoglobulin fold family.

Protein engineering - 1 Nov 2002

Valerio-Lepiniec Marielle, Nicaise Magali, Adjadj Elisabeth, Minard Philippe, Desmadril Michel

Abstract excerpt

Neocarzinostatin (NCS) is a seven-stranded beta-sandwich protein, the folding of which is similar to that of the variable domains of immunoglobulins (Ig). The investigation of the backbone dynamics of apo-NCS [Izadi-Pruneyre et al. (2001) Protein Sci., 10, 2228-2240] enabled us to identify the involvement of long side-chain residues in maintaining the rigidity of this beta-protein. In the perspective of using...

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Identifiers

PMID: 12538905
DOI: 10.1093/protein/15.11.861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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