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Article

Role of the tyrosine corner motif in the stability of neocarzinostatin.

Protein engineering - 1 Oct 2003

Nicaise Magali, Valerio-Lepiniec Marielle, Izadi-Pruneyre Nadia, Adjadj Elisabeth, Minard Philippe, Desmadril Michel

Abstract excerpt

Although the immunoglobulin-like beta-sandwich fold has no specifically conserved function, some common structural features have been observed, in particular a structural motif, the tyrosine corner. Such a motif was described in neocarzinostatin (NCS), a bacterial protein the structure of which is very similar to that of the immunoglobulin domain. Compared with the other beta-sheet proteins, the NCS 'tyrosine...

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Identifiers

PMID: 14600202
DOI: 10.1093/protein/gzg099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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