Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila D1 dopamine receptor mediates caffeine-induced arousal.

Proceedings of the National Academy of Sciences of the United States of America - 23 Dec 2008

Andretic Rozi, Kim Young-Cho, Jones Frederick S, Han Kyung-An, Greenspan Ralph J

Abstract excerpt

The arousing and motor-activating effects of psychostimulants are mediated by multiple systems. In Drosophila, dopaminergic transmission is involved in mediating the arousing effects of methamphetamine, although the neuronal mechanisms of caffeine (CAFF)-induced wakefulness remain unexplored. Here, we show that in Drosophila, as in mammals, the wake-promoting effect of CAFF involves both the adenosinergic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine
Share to Arousal
Share to Caffeine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine

Share to Methamphetamine

Share to Neurotransmitter Agents

Share to Organisms, Genetically Modified

Share to Receptors, Dopamine

Source

Open in PubMed Open full text

Identifiers

PMID: 19074291
DOI: 10.1073/pnas.0806776105
PMCID: PMC2629270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila D1 dopamine receptor mediates caffeine-induced arousal.PMID 19074291Read ↗

Dopaminergic modulation of arousal in Drosophila.Semantic proximity Read ↗

Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.Semantic proximity Read ↗

The Use of Drosophila to Understand Psychostimulant ResponsesSemantic proximity Read ↗

Circasemidian, circadian, and longer-period activity rhythms in caffeine-treated molecular clock deficient cryptochrome (Cry) 1 and Cry 2 double knockout miceSemantic proximity Read ↗

Genetics of Cocaine and Methamphetamine Consumption and Preference in <i>Drosophila melanogaster</i>Semantic proximity Read ↗

A Genetic Screen To Assess Dopamine Receptor (DopR1) Dependent Sleep Regulation in Drosophila.Semantic proximity Read ↗

Dopamine is a regulator of arousal in the fruit fly.Semantic proximity Read ↗

Identification of a dopamine pathway that regulates sleep and arousal in Drosophila.Semantic proximity Read ↗

A regulatory pathway linking caffeine action, mood and the diurnal clock.Semantic proximity Read ↗

Dopaminergic role in regulating neurophysiological markers of sleep homeostasis in humans.Semantic proximity Read ↗

RNAi-based screen for pigmentation in <i>Drosophila melanogaster</i> reveals regulators of brain dopamine and sleepSemantic proximity Read ↗

Sleep and wakefulness in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.