Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interleukin-1 gene complex polymorphisms in systemic sclerosis patients with severe restrictive lung physiology.

Human immunology - 1 Jul 2007

Beretta Lorenzo, Bertolotti Francesca, Cappiello Francesca, Barili Morena, Masciocchi Michela, Toussoun Karen, Caronni Monica, Scorza Raffaella

Abstract excerpt

Increased concentrations of interleukin-1 (IL-1) were observed in bronchoalveolar lavage fluids from patients with systemic sclerosis (SSc), and their levels were correlated with the patients' forced vital capacity (FVC). Because IL-1 production is regulated at the genetic level, we hypothesized that IL-1 gene complex single nucleotide polymorphisms (SNPs) might be relevant to the progression of ventilatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchoalveolar Lavage Fluid
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1alpha

Share to Interleukin-1beta

Share to Lung Diseases, Obstructive

Share to Regression Analysis

Share to Scleroderma, Systemic

Source

Identifiers

PMID: 17584583
DOI: 10.1016/j.humimm.2007.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interleukin-1 gene complex polymorphisms in systemic sclerosis patients with severe restrictive lung physiology.PMID 17584583Read ↗

Interleukin-1 gene complex single nucleotide polymorphisms in systemic sclerosis: a further step ahead.Semantic proximity Read ↗

IL-1A rs1800587, IL-1B rs1143634 and IL-1R1 rs2234650 polymorphisms in Iranian patients with systemic sclerosis.Semantic proximity Read ↗

Association of interleukin-1 family cytokines single nucleotide polymorphisms with susceptibility to systemic sclerosis: an independent case-control study and a meta-analysis.Semantic proximity Read ↗

NLRP1 influences the systemic sclerosis phenotype: a new clue for the contribution of innate immunity in systemic sclerosis-related fibrosing alveolitis pathogenesis.Semantic proximity Read ↗

Interleukin-1 gene cluster and IL-1 receptor polymorphisms in Iranian patients with systemic lupus erythematosus.Semantic proximity Read ↗

Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis.Semantic proximity Read ↗

T-889C IL-1alpha promoter polymorphism influences the response to oral cyclophosphamide in scleroderma patients with alveolitis.Semantic proximity Read ↗

Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients.Semantic proximity Read ↗

Association of IL1A gene polymorphisms with susceptibility to and severity of systemic sclerosis in the Japanese population.Semantic proximity Read ↗

Analysis of IL6 and IL1A gene polymorphisms in UK and Dutch patients with sarcoidosis.Semantic proximity Read ↗

Interleukin 1alpha single-nucleotide polymorphism associated with systemic sclerosis.Semantic proximity Read ↗

Angiotensin-converting enzyme 1 gene polymorphisms in patients with systemic sclerosis-associated interstitial lung disease: a single centre retrospective observational study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.