Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the tyrosine hydroxylase gene in subjects susceptible to high-altitude pulmonary edema.

Chest - 1 Jan 2003

Hanaoka Masayuki, Droma Yunden, Hotta Junichi, Matsuzawa Yukinori, Kobayashi Toshio, Kubo Keishi, Ota Masao

Abstract excerpt

STUDY OBJECTIVES: A blunted hypoxic ventilatory response (HVR) has been observed in some sufferers of high-altitude pulmonary edema (HAPE), and was proposed as a potential mechanism in its pathogenesis. Tyrosine hydroxylase (TH) is a rate-limiting enzyme in the carotid body responding to hypoxia to synthesize dopamine neurotransmitter to heighten ventilation. The association of constitutional susceptibility to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Altitude

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cross-Sectional Studies

Share to Microsatellite Repeats

Share to Polymorphism, Genetic

Share to Tyrosine 3-Monooxygenase

Source

Identifiers

PMID: 12527603
DOI: 10.1378/chest.123.1.54

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the tyrosine hydroxylase gene in subjects susceptible to high-altitude pulmonary edema.PMID 12527603Read ↗

Gene polymorphisms and high-altitude pulmonary edema susceptibility: a 2011 update.Semantic proximity Read ↗

Polymorphisms of human vascular endothelial growth factor gene in high-altitude pulmonary oedema susceptible subjects.Semantic proximity Read ↗

Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edema.Semantic proximity Read ↗

Genetic Predisposition to High-Altitude Pulmonary Edema.Semantic proximity Read ↗

Rare mitochondrial DNA polymorphisms are associated with high altitude pulmonary edema (HAPE) susceptibility in Han Chinese.Semantic proximity Read ↗

Polymorphisms of renin-angiotensin system genes with high-altitude pulmonary edema in Japanese subjects.Semantic proximity Read ↗

Angiotensin II receptor 1 gene variants are associated with high-altitude pulmonary edema risk.Semantic proximity Read ↗

Association of polymorphisms in angiotensin and aldosterone synthase genes of the renin-angiotensin-aldosterone system with high-altitude pulmonary edema.Semantic proximity Read ↗

Telomere length-related gene ACYP2 polymorphism is associated with the risk of HAPE in Chinese Han population.Semantic proximity Read ↗

[Genetic susceptibility for acute high altitude disease].Semantic proximity Read ↗

No relation between ACE-I/D polymorphism and high altitude pulmonary edema in the Han Chinese.Semantic proximity Read ↗

Association of variants m.T16172C and m.T16519C in whole mtDNA sequences with high altitude pulmonary edema in Han Chinese lowlandersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.