Article
Polymorphisms of human vascular endothelial growth factor gene in high-altitude pulmonary oedema susceptible subjects.
Respirology (Carlton, Vic.) - 1 Jan 2009
Hanaoka Masayuki, Droma Yunden, Ota Masao, Ito Michiko, Katsuyama Yoshihiko, Kubo Keishi
Abstract excerpt
BACKGROUND AND OBJECTIVE: Based on the reported biological properties and function of vascular endothelial growth factor (VEGF) in hypoxic conditions, many investigations have studied the hypothesis that VEGF has an important role in the pathogenesis of high altitude sicknesses, including high-altitude pulmonary oedema (HAPE). Unfortunately, the results are inconsistent. Therefore, the association of VEGF gene...
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