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Article

Rare mitochondrial DNA polymorphisms are associated with high altitude pulmonary edema (HAPE) susceptibility in Han Chinese.

Wilderness & environmental medicine - 1 Jun 2012

Luo Yongjun, Gao Wenxiang, Chen Yu, Liu Fuyu, Gao Yuqi

Abstract excerpt

BACKGROUND: The role of genetics in determining an individual's susceptibility to high altitude pulmonary edema (HAPE) is unclear. However a number of genetic polymorphisms have recently been found to be overrepresented in patients with HAPE. Changes at the mitochondrial level may play an important role in the human body's adaptation to hypoxia. Polymorphisms of mitochondrial DNA (mtDNA) have been shown to be...

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Identifiers

PMID: 22656658
DOI: 10.1016/j.wem.2012.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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