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Article

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients.

Neuroscience letters - 30 Jan 2003

Mattila Kari M, Hiltunen Mikko, Rinne Juha O, Mannermaa Arto, Röyttä Matias, Alafuzoff Irina, Laippala Pekka, Soininen Hilkka, Lehtimäki Terho

Abstract excerpt

Increased expression of intercellular adhesion molecule 1 (ICAM1), a protein known to contribute to inflammatory responses, has been detected in the brain tissue of patients with Alzheimer's disease (AD) and animals modelled to mimic AD or Parkinson's disease (PD). ICAM1 may, thus, be implicated in the pathogenesis of these disorders. Our purpose was to investigate whether genetic variants of the ICAM1 gene have...

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Source

Identifiers

PMID: 12524171
DOI: 10.1016/s0304-3940(02)01296-x

Genes

ICAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients.PMID 12524171Read ↗

Intercellular adhesion molecule-1 K469E gene polymorphism and Alzheimer's disease.Semantic proximity Read ↗

Polymorphism at codon 469 of the intercellular adhesion molecule-1 gene is not associated with sporadic Alzheimer's disease.Semantic proximity Read ↗

Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism: no association with type 1 diabetes among Finns.Semantic proximity Read ↗

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Intercellular adhesion molecule-1 K469E polymorphism: study of association with multiple sclerosis.Semantic proximity Read ↗

The K469E polymorphism of the ICAM-1 gene is a risk factor for peripheral arterial occlusive disease.Semantic proximity Read ↗

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The intercellular adhesion molecule-1 (ICAM-1) gene K469E polymorphism is not associated with ischaemic heart disease: an investigation using family-based tests of association.Semantic proximity Read ↗

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