Article
The K469E polymorphism of the ICAM-1 gene is a risk factor for peripheral arterial occlusive disease.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2002
Gaetani E, Flex A, Pola R, Papaleo P, De Martini D, Pola E, Aloi F, Flore R, Serricchio M, Gasbarrini A, Pola P
Abstract excerpt
Intercellular adhesion molecule-1 (ICAM-1) plays a crucial role in lymphocyte migration and activation, and is considered important in the pathogenesis of atherosclerosis. K469E is a common polymorphism of the ICAM-1 gene with potential functional significance. The aim of the present case-control study was to evaluate the association between this polymorphism and peripheral arterial occlusive disease (PAOD)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.