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Article

Intercellular adhesion molecule-1 K469E gene polymorphism and Alzheimer's disease.

Neurobiology of aging - 1 Jan 2000

Pola Roberto, Flex Andrea, Gaetani Eleonora, Santoliquido Angelo, Serricchio Michele, Pola Paolo, Bernabei Roberto

Abstract excerpt

Inflammatory processes are considered important in the pathogenesis of Alzheimer's disease (AD). Intercellular adhesion molecule-1 (ICAM-1) is an important mediator of inflammatory response and immune cell activation, is expressed on cerebrovascular endothelium and neuritic plaques in brain of AD patients, and seems to be implicated in the process of neuro-degeneration. A common polymorphism of the ICAM-1 gene...

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PMID: 12498973
DOI: 10.1016/s0197-4580(02)00087-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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