Article
Association between intercellular adhesion molecule-1 E/K gene polymorphism and probable vascular dementia in humans.
Neuroscience letters - 5 Jul 2002
Pola Roberto, Flex Andrea, Gaetani Eleonora, Papaleo Pierangelo, De Martini Demetrio, Gerardino Laura, Serricchio Michele, Pola Paolo, Bernabei Roberto
Abstract excerpt
Intercellular adhesion molecule-1 (ICAM-1) is implicated in the pathogenesis of ischemic cardiovascular disorders, including cerebral ischemia. A common polymorphism of the ICAM-1 gene (K469E) has been recently reported. In this case-control study, we evaluated the association between this polymorphism and vascular dementia (VD) by studying 107 patients affected by probable VD and 115 age- and sex-matched...
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