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Article

Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans.

The Journal of rheumatology - 1 Jan 2003

Oates Jim C, Levesque Marc C, Hobbs Maurine R, Smith Erica Grace, Molano Ivan D, Page Grier P, Hill Bruce S, Weinberg J Brice, Cooper Glinda S, Gilkeson Gary S

Abstract excerpt

OBJECTIVE: Systemic lupus erythematosus (SLE) is an autoimmune disease in which morbidity and mortality are higher in African-Americans. The etiology of this racial disparity is unknown. A genetic predisposition to enhanced nitric oxide (NO) production may predispose African-Americans to develop SLE and may increase disease severity. We have demonstrated a correlation between NO production and disease activity in...

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Identifiers

PMID: 12508391

Genes

NOS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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