Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced neuronal nitric oxide synthase expression is central to cardiac vagal phenotype in exercise-trained mice.

The Journal of physiology - 1 Jan 2003

Danson E J F, Paterson D J

Abstract excerpt

We investigated whether enhanced cardiac vagal responsiveness elicited by exercise training is dependent on neuronal nitric oxide synthase (NOS-1), since the NO-cGMP pathway facilitates acetylcholine release. Isolated atria with intact right vagal innervation were taken from male mice (18-22 weeks old) after a period of 10 weeks voluntary wheel-running (+EX, n = 27; peaked 9.8 +/- 0.6 km day(-1) at 5 weeks), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclic GMP
Share to Guanylate Cyclase
Share to Nitric Oxide Donors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type I

Share to Nitroprusside

Share to Physical Conditioning, Animal

Share to Vagus Nerve

Source

Open in PubMed Open full text

Identifiers

PMID: 12509490
DOI: 10.1113/jphysiol.2002.031781
PMCID: PMC2342466

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced neuronal nitric oxide synthase expression is central to cardiac vagal phenotype in exercise-trained mice.PMID 12509490Read ↗

Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele.Semantic proximity Read ↗

Myocardial contractile function and heart rate in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.Semantic proximity Read ↗

Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases.Semantic proximity Read ↗

Disruption of Physiological Balance Between Nitric Oxide and Endothelium-Dependent Hyperpolarization Impairs Cardiovascular Homeostasis in Mice.Semantic proximity Read ↗

Circadian rhythms in heart rate, motility, and body temperature of wild-type C57 and eNOS knock-out mice under light-dark, free-run, and after time zone transition.Semantic proximity Read ↗

Comparison of changes in electrical activity, in isolated and <i>in vivo</i> hearts, induced by voluntary exercise in female ratsSemantic proximity Read ↗

Phenotypic screening for heart rate variability in the mouse.Semantic proximity Read ↗

Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype.Semantic proximity Read ↗

Nicotine induces a long QT phenotype in Kcnq1-deficient mouse hearts.Semantic proximity Read ↗

Nitric oxide release and contractile properties of skeletal muscles from mice deficient in type III NOS.Semantic proximity Read ↗

Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice.Semantic proximity Read ↗

Heart rate dynamics in monoamine oxidase-A- and -B-deficient mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.