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Detection of HLA polymorphisms by ligase detection reaction and a universal array format: a pilot study for low resolution genotyping.

Human immunology - 1 Jan 2003

Consolandi Clarissa, Busti Elena, Pera Cinzia, Delfino Laura, Ferrara Gian Battista, Bordoni Roberta, Castiglioni Bianca, Bernardi Luigi Rossi, Battaglia Cristina, De Bellis Gianluca

Abstract excerpt

We present our results in the identification of polymorphic sites within the second exon of the human leukocyte antigen A (HLA-A) region using the DNA microarray technology. Allele specific detection was performed by polymerase chain reaction followed by ligase detection reaction (LDR) in combination with a universal array, a powerful method for high throughput DNA sequence analysis. By this approach we confirmed...

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PMID: 12507828
DOI: 10.1016/s0198-8859(02)00685-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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