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Article

A multiplex single nucleotide polymorphism genotyping method using ligase-based mismatch discrimination and CE-SSCP.

Electrophoresis - 1 Apr 2014

Choi Woong, Shin Gi Won, Hwang Hee Sung, Pack Seung Pil, Jung Gyu Yong, Jung Gyoo Yeol

Abstract excerpt

Accuracy, simplicity, and cost-effectiveness are the most important criteria for a genotyping method for SNPs compatible with clinical use. One method developed for SNP genotyping, ligase-based discrimination, is considered the simplest for clinical diagnosis. However, multiplex assays using this method are limited by the detection method. Although CE has been introduced as an alternative to error prone...

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PMID: 24452927
DOI: 10.1002/elps.201300486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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