Article
[Relationship between core gene mutations of hepatitis B virus and response to alpha interferon therapy in chronic hepatitis B].
Taehan Kan Hakhoe chi = The Korean journal of hepatology - 1 Dec 2002
Yoo Byung Chul, Kim Hyung Joon, Do Jae Hyuk, Park Sill Moo
Abstract excerpt
BACKGROUND/AIMS: Treatment of chronic hepatitis B with interferon results in a sustained loss of hepatitis B virus DNA and hepatitis B e antigen (HBeAg) and remission of liver disease only in a proportion of cases. Recently, mutations of hepatitis B virus (HBV) core gene have been reported as being related to the failure of interferon treatment in chronic hepatitis B. This study investigated whether core gene...
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