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Article

[Detection and characterization of pre-core mutants of hepatitis B virus (HBV) in chronically infected patients].

Acta gastroenterologica Latinoamericana - 1 Jan 1995

López J L, Telenta P F, Palacios Poggio González J, Alonso A G, Lemberg A, Campos R

Abstract excerpt

Hepatitis B virus infection is responsible of an important number of world morbimortality. This is associated to severe liver outcome such as cirrhosis and hepatocellular carcinoma. Diverse factors influence the severity of liver injury produced by Hepatitis B Virus (HBV): the emergence of HBV mutants unable to secrete "e" antigen (pre-core mutants), the virus and host genetic heterogenicity and immune system...

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PMID: 8525764

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