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Article

The role of neutralizing antibodies for mouse mammary tumor virus transmission and mammary cancer development.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 2003

Finke Daniela, Luther Sanjiv A, Acha-Orbea Hans

Abstract excerpt

Mouse mammary tumor virus (MMTV) infection establishes chronic germinal centers and a lifelong neutralizing Ab response. We show that removal of the draining lymph node after establishment of the germinal center reaction led to complete loss of neutralizing Abs despite comparable infection levels in peripheral lymphocytes. Importantly, in the absence of neutralization, only the exocrine organs mammary gland,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mammary Neoplasms, Experimental

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Share to Mice, Inbred BALB C

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Identifiers

PMID: 12502785
DOI: 10.1073/pnas.0134988100
PMCID: PMC140926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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