Article
CDK5 regulates cell adhesion and migration in corneal epithelial cells.
Molecular cancer research : MCR - 1 Nov 2002
Gao Chun, Negash Sewite, Guo Hong Tao, Ledee Dolena, Wang Hwai-Shi, Zelenka Peggy
Abstract excerpt
CDK5 and its activator, p35, are expressed in mouse corneal epithelium and can be coimmunoprecipited from corneal epithelial cell lysates. Immunostaining shows CDK5 and p35 in all layers of the corneal epithelium, especially along the basal side of the basal cells. Stable transfection of corneal epithelial cells with CDK5, which increases CDK5 kinase activity by approximately 33%, also increases the number of...
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