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Article

Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jun 2010

Poore Charlene P, Sundaram Jeyapriya R, Pareek Tej K, Fu Amy, Amin Niranjana, Mohamed Nur Ezan, Zheng Ya-Li, Goh Angeline X H, Lai Mitchell K, Ip Nancy Y, Pant Harish C, Kesavapany Sashi

Abstract excerpt

Cyclin-dependent kinase 5 (Cdk5)-mediated phosphorylation plays an important role in proper synaptic function and transmission. Loss of Cdk5 activity results in abnormal development of the nervous system accompanied by massive disruptions in cortical migration and lamination, therefore impacting synaptic activity. The Cdk5 activator p35 associates with delta-catenin, the synaptic adherens junction protein that...

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Identifiers

PMID: 20573893
DOI: 10.1523/JNEUROSCI.6062-09.2010
PMCID: PMC5283092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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