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Article

The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7.

The Journal of biological chemistry - 28 Feb 2003

Hyland Edel M, Rezende Lisa F, Richardson Charles C

Abstract excerpt

Gene 2.5 of bacteriophage T7 encodes a single-stranded DNA-binding protein that is essential for viral survival. Its crystal structure reveals a conserved oligosaccharide/oligonucleotide binding fold predicted to interact with single-stranded DNA. However, there is no experimental evidence to support this hypothesis. Recently, we reported a genetic screen for lethal mutations in gene 2.5 that we are using to...

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Identifiers

PMID: 12496273
DOI: 10.1074/jbc.M210605200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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