Article
Lipooligosaccharide-deficient Neisseria meningitidis shows altered pilus-associated characteristics.
Infection and immunity - 1 Jan 2003
Albiger Barbara, Johansson Linda, Jonsson Ann-Beth
Abstract excerpt
Molecular interaction between host mucosal surfaces and outer membrane components of microbes is crucial in the infection process. The outer membrane of pathogenic Neisseria contains surface molecules such as pili, PilC, and Opa and a monolayer of lipooligosaccharide (LOS), all of which are involved in the interaction with host cells. Pili mediate the initial attachment to human epithelial cells, which is...
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