Article
The number of Neisseria meningitidis type IV pili determines host cell interaction.
The EMBO journal - 18 Aug 2014
Imhaus Anne-Flore, Duménil Guillaume
Abstract excerpt
As mediators of adhesion, autoaggregation and bacteria-induced plasma membrane reorganization, type IV pili are at the heart of Neisseria meningitidis infection. Previous studies have proposed that two minor pilins, PilV and PilX, are displayed along the pilus structure and play a direct role in mediating these effects. In contrast with this hypothesis, combining imaging and biochemical approaches we found that...
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