Article
Expression of type IV pili by Moraxella catarrhalis is essential for natural competence and is affected by iron limitation.
Infection and immunity - 1 Nov 2004
Luke Nicole R, Howlett Amy J, Shao Jianqiang, Campagnari Anthony A
Abstract excerpt
Type IV pili, filamentous surface appendages primarily composed of a single protein subunit termed pilin, play a crucial role in the initiation of disease by a wide range of pathogenic bacteria. Although previous electron microscopic studies suggested that pili might be present on the surface of Moraxella catarrhalis isolates, detailed molecular and phenotypic analyses of these structures have not been reported...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Humans
- Iron
- Molecular Sequence Data
- Moraxella catarrhalis
- Mutation
- Nucleoside-Triphosphatase
- Repressor Proteins
- Reverse Transcriptase Polymerase Chain Reaction