Large‐scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis : characterization of a subcomplex involved in pilus assembly

Abstract excerpt

The functionally versatile type IV pili (Tfp) are one of the most widespread virulence factors in bacteria. However, despite generating much research interest for decades, the molecular mechanisms underpinning the various aspects of Tfp biology remain poorly understood, mainly because of the complexity of the system. In the human pathogen Neisseria meningitidis for example, 23 proteins are dedicated to Tfp...

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