Article
Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function.
Molecular microbiology - 1 Jan 2005
Carbonnelle Etienne, Hélaine Sophie, Prouvensier Laure, Nassif Xavier, Pelicic Vladimir
Abstract excerpt
Type IV pili (Tfp) play a critical role in the pathogenic lifestyle of Neisseria meningitidis and N. gonorrhoeae, notably by facilitating bacterial attachment to human cells, but our understanding of their biogenesis, during which the fibres are assembled in the periplasm, then emerge onto the cell surface and are stabilized, remains fragmentary. We therefore sought to identify the genes required for Tfp...
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