Article
Lipooligosaccharide-independent alteration of cellular homeostasis in Neisseria meningitidis-infected epithelial cells.
Cellular microbiology - 1 Jun 2005
Bonnah Robert A, Hoelter Jenny, Steeghs Liana, Enns Caroline A, So Magdalene, Muckenthaler Martina U
Abstract excerpt
Neisseria meningitidis (MC) is an important cause of meningitis and septic shock. Primary loose attachment of MC to host epithelial cells is mediated by type IV pili. Lipooligosaccharide (LOS), opacity (Opa) proteins and glycolipid adhesins facilitate subsequent tight attachment. MC infection causes numerous changes in host epithelial cell homeostasis. These include cortical plaque formation, increased expression...
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