Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein.

Neuron - 19 Dec 2002

Stowers R Steven, Megeath Laura J, Górska-Andrzejak Jolanta, Meinertzhagen Ian A, Schwarz Thomas L

Abstract excerpt

A protein required to localize mitochondria to Drosophila nerve terminals has been identified genetically. Photoreceptors mutant for milton show aberrant synaptic transmission despite normal phototransduction. Without Milton, synaptic terminals and axons lack mitochondria, although mitochondria are numerous in neuronal cell bodies. In contrast, synaptic vesicles continue to be transported to and concentrated at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axonal Transport
Share to Kinesins
Share to Microscopy, Electron

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nervous System Malformations

Share to Photoreceptor Cells, Invertebrate

Share to Presynaptic Terminals

Share to Sequence Homology, Nucleic Acid

Share to Synaptic Transmission

Source

Identifiers

PMID: 12495622
DOI: 10.1016/s0896-6273(02)01094-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein.PMID 12495622Read ↗

The myriad roles of Miro in the nervous system: axonal transport of mitochondria and beyondSemantic proximity Read ↗

The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.Semantic proximity Read ↗

ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss.Semantic proximity Read ↗

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondriaSemantic proximity Read ↗

Syntabulin-mediated anterograde transport of mitochondria along neuronal processes.Semantic proximity Read ↗

Metaxin-2 tunes mitochondrial transportation and neuronal function in DrosophilaSemantic proximity Read ↗

CRMP/UNC-33 organizes microtubule bundles for KIF5-mediated mitochondrial distribution to axon.Semantic proximity Read ↗

Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.Semantic proximity Read ↗

UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport.Semantic proximity Read ↗

Mitf contributes to melanosome distribution and melanophore dendricity.Semantic proximity Read ↗

Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction.Semantic proximity Read ↗

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.