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Metaxin-2 tunes mitochondrial transportation and neuronal function in Drosophila

5 Dec 2024

Abstract excerpt

Metaxins are a family of evolutionarily conserved proteins that reside on the mitochondria outer membrane (MOM) and participate in the protein import into the mitochondria. Metaxin-2 (Mtx2), a member of this family, has been identified as a key component in the machinery for mitochondrial transport in both C. elegans and human neurons. To deepen our understanding of Mtx2's role in neurons, we examined the...

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PMID: 39657051
DOI: 10.1093/genetics/iyae204

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