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Article

Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells.

1 Jan 2002

Abstract excerpt

BACKGROUND: The interaction of nuclear and mitochondrial genes is an essential feature in maintenance of normal cellular function. Of 82 structural subunits that make up the oxidative phosphorylation system in the mitochondria, mitochondrial DNA (mtDNA) encodes 13 subunits and rest of the subunits are encoded by nuclear DNA. Mutations in mitochondrial genes encoding the 13 subunits have been reported in a variety...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12495447
DOI: 10.1186/1476-4598-1-6

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