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Article

Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer.

Cancer biology & therapy - 1 Aug 2006

Kulawiec Mariola, Arnouk Hilal, Desouki Mohamed Mokhtar, Kazim Latif, Still Ivan, Singh Keshav K

Abstract excerpt

All tumors examined to date contain mutations in mitochondrial DNA (mtDNA). In addition, depletion of mtDNA is reported in a variety of tumors. Mitochondrial dysfunction resulting from changes in mtDNA invokes mitochondria-to-nucleus retrograde response in human cells. To identify proteins involv...

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Identifiers

PMID: 16775426
DOI: 10.4161/cbt.5.8.2880

Genes

UQCRC1
IMPDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16775426-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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