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Article

Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome.

International journal of cancer - 20 Feb 2003

Kielhorn Eric, Provost Elayne, Olsen Drew, D'Aquila Thomas G, Smith Bradley L, Camp Robert L, Rimm David L

Abstract excerpt

Beyond depth of invasion, there are very few prognostic markers to predict outcome in melanoma. It has been shown recently that the beta-catenin oncogene is mutated or shows altered subcellular localization suggesting that activation of beta-catenin mediated signaling plays a role in oncogenesis. We hypothesize that assessment of activated beta-catenin, as detected by a phospho-specific antibody, may be useful to...

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Source

Identifiers

PMID: 12494474
DOI: 10.1002/ijc.10893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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