Article
Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas.
Cancer research - 1 Apr 1998
Palacios J, Gamallo C
Abstract excerpt
Mutations of the beta-catenin gene (CTNNB1) have recently been implicated in the initiation of some colon carcinomas and melanomas. In these tumors, beta-catenin abnormally accumulates in the cell nuclei. In an ongoing immunohistochemical study of the cadherin-catenin complex protein expression in ovarian carcinomas, we observed beta-catenin in tumor cell nuclei in some cases; this prompted us to study whether or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
