Article
The immunogenomics of minor histocompatibility antigens.
Immunological reviews - 1 Dec 2002
Roopenian Derry, Choi Eun Young, Brown Aaron
Abstract excerpt
Minor histocompatibility (H) antigens are a diverse assemblage of major histocompatibility complex (MHC)-bound peptides with the unifying property of acting as alloantigens that induce allogeneic tissue rejection. They are a consequence of any form of accumulated genetic variation that translates to differential MHC-presented peptide epitopes, the most common form of which is simple sequence polymorphisms. The...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Genetic Variation
- Genomics
- Graft Rejection
- H-Y Antigen
- Humans
- Major Histocompatibility Complex
- Male
- Mice
- Minor Histocompatibility Loci
- Models, Immunological
- Molecular Sequence Data
- Transplantation, Homologous
