Article
Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex.
Immunity - 1 Oct 1997
Mendoza L M, Paz P, Zuberi A, Christianson G, Roopenian D, Shastri N
Abstract excerpt
The products of minor histocompatibility (H) loci are serious barriers to tissue transplantation even among major histocompatibility complex (MHC) identical individuals, frequently causing chronic graft rejection and graft versus host disease. Over 50 minor H loci map to mouse autosomal chromosomes but none are known at the molecular level. By expression cloning, we identified the H13 locus, a classical minor H...
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