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Article

In vivo functional dissection of human inner kinetochore protein CENP-C.

Journal of structural biology - 1 Jan 2000

Trazzi Stefania, Bernardoni Roberto, Diolaiti Daniel, Politi Valeria, Earnshaw William C, Perini Giovanni, Della Valle Giuliano

Abstract excerpt

CENP-C is a fundamental component of the inner kinetochore plate and contributes to the formation of functional centromeres in eukaryotic organisms. Recruitment of CENP-C to kinetochore requires other centromere proteins, particularly CENP-A, CENP-H, and CENP-I. However, how CENP-C is correctly localized at the kinetochore is not clearly determined, mainly due to the functional variety of its domains, which hints...

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Identifiers

PMID: 12490152
DOI: 10.1016/s1047-8477(02)00506-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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