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Article

Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons.

The Journal of biological chemistry - 28 Feb 2003

Cheng Aiwu, Wang Shuqin, Yang Dongmei, Xiao Ruiping, Mattson Mark P

Abstract excerpt

As a calcium-sensing protein, calmodulin acts as a transducer of the intracellular calcium signal for a variety of cellular responses. Although calcium is an important regulator of neuronal survival during development of the nervous system and is also implicated in the pathogenesis of neurodegenerative disorders, it is not known if calmodulin mediates these actions of calcium. To determine the role of calmodulin...

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Source

Identifiers

PMID: 12488453
DOI: 10.1074/jbc.M207232200

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons.PMID 12488453Read ↗

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