Article
Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels.
PloS one - 25 Jul 2007
Sangster Todd A, Bahrami Adam, Wilczek Amity, Watanabe Etsuko, Schellenberg Kurt, McLellan Catherine, Kelley Alicia, Kong Sek Won, Queitsch Christine, Lindquist Susan
Abstract excerpt
The molecular chaperone HSP90 aids the maturation of a diverse but select set of metastable protein clients, many of which are key to a variety of signal transduction pathways. HSP90 function has been best investigated in animal and fungal systems, where inhibition of the chaperone has exceptionally diverse effects, ranging from reversing oncogenic transformation to preventing the acquisition of drug resistance....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.