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Article

Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons.

Nature - 4 Feb 2010

Specchia Valeria, Piacentini Lucia, Tritto Patrizia, Fanti Laura, D'Alessandro Rosalba, Palumbo Gioacchino, Pimpinelli Sergio, Bozzetti Maria P

Abstract excerpt

The canalization concept describes the resistance of a developmental process to phenotypic variation, regardless of genetic and environmental perturbations, owing to the existence of buffering mechanisms. Severe perturbations, which overcome such buffering mechanisms, produce altered phenotypes t...

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PMID: 20062045
DOI: 10.1038/nature08739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20062045-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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