Article
Importance of B-cell responses for immunological control of variant strains of simian immunodeficiency virus.
Journal of virology - 1 Jan 2003
Johnson Welkin E, Lifson Jeffrey D, Lang Sabine M, Johnson R Paul, Desrosiers Ronald C
Abstract excerpt
The properties of three variants of cloned simian immunodeficiency virus strain 239 (SIV239) were compared. One strain (M5) lacked five sites for N-linked carbohydrate attachment in variable regions 1 and 2 (V1 and V2) of the gp120 envelope protein, one strain (DeltaV1-V2) completely lacked V1 and V2 sequences, and another (316) had nine mutations in the envelope that impart high replicative capacity for tissue...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
