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Article

Antigenic variation of SIV: mutations in V4 alter the neutralization profile.

Virology - 1 Jul 1996

Kinsey N E, Anderson M G, Unangst T J, Joag S V, Narayan O, Zink M C, Clements J E

Abstract excerpt

Antigenic variation is a characteristic feature of lentiviral infection. The SIV/macaque model of AIDS provides an ideal system in which to investigate the molecular basis of antigenic variation. The purpose of this study was to genetically map the nucleotide changes in env that alter the neutralization phenotype of SIV. Serum taken from an SIVmac239-infected macaque (2D) at 30 weeks postinoculation was found to...

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Identifiers

PMID: 8661410
DOI: 10.1006/viro.1996.0348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Antigenic variation of SIV: mutations in V4 alter the neutralization profile.PMID 8661410Read ↗

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