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Article

Heterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock.

Journal of virology - 1 May 2013

Lopker Michael, Easlick Juliet, Sterrett Sarah, Decker Julie M, Barbian Hannah, Learn Gerald, Keele Brandon F, Robinson James E, Li Hui, Hahn Beatrice H, Shaw George M, Bar Katharine J

Abstract excerpt

The sooty mangabey-derived simian immunodeficiency virus (SIV) strain E660 (SIVsmE660) is a genetically heterogeneous, pathogenic isolate that is commonly used as a vaccine challenge strain in the nonhuman primate (NHP) model of human immunodeficiency virus type 1 (HIV-1) infection. Though it is often employed to assess antibody-based vaccine strategies, its sensitivity to antibody-mediated neutralization has not...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23468494
DOI: 10.1128/JVI.03419-12
PMCID: PMC3648171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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