MOESIN crosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring.

doi:10.1016/s0960-9822(02)01256-3

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Article

MOESIN crosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring.

Current biology : CB - 10 Dec 2002

Jankovics Ferenc, Sinka Rita, Lukácsovich Tamás, Erdélyi Miklós

Abstract excerpt

In Drosophila, development of the embryonic germ cells depends on posterior transport and site-specific translation of oskar (osk) mRNA and on interdependent anchoring of the osk mRNA and protein within the posterior subcortical region of the oocyte. Transport of the osk mRNA is mediated by microtubules, while anchoring of the osk gene products at the posterior pole of the oocyte is suggested to be microfilament...

Topics

Actins
Animals
Base Sequence
Cell Membrane
Cloning, Molecular
DNA Primers
Drosophila
Drosophila Proteins
Female
In Situ Hybridization
Membrane Proteins
Microtubules
Oocytes
Phenotype
Polymerase Chain Reaction
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 12477397
DOI: 10.1016/s0960-9822(02)01256-3

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