Article
Opposing roles for Egalitarian and Staufen in transport, anchoring and localization of oskar mRNA in the Drosophila oocyte.
PLoS genetics - 1 Apr 2021
Mohr Sabine, Kenny Andrew, Lam Simon T Y, Morgan Miles B, Smibert Craig A, Lipshitz Howard D, Macdonald Paul M
Abstract excerpt
Localization of oskar mRNA includes two distinct phases: transport from nurse cells to the oocyte, a process typically accompanied by cortical anchoring in the oocyte, followed by posterior localization within the oocyte. Signals within the oskar 3' UTR directing transport are individually weak, a feature previously hypothesized to facilitate exchange between the different localization machineries. We show that...
Topics
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Inverted Repeat Sequences
- Mutation
- Oocytes
- RNA-Binding Proteins
