Article
A new isoform of Drosophila non-muscle Tropomyosin 1 interacts with Kinesin-1 and functions in oskar mRNA localization.
Journal of cell science - 15 Nov 2016
Veeranan-Karmegam Rajalakshmi, Boggupalli Devi Prasad, Liu Guojun, Gonsalvez Graydon B
Abstract excerpt
Recent studies have revealed that diverse cell types use mRNA localization as a means to establish polarity. Despite the prevalence of this phenomenon, much less is known regarding the mechanism by which mRNAs are localized. The Drosophila melanogaster oocyte provides a useful model for examining the process of mRNA localization. oskar (osk) mRNA is localized at the posterior of the oocyte, thus restricting the...
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