Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.

Development (Cambridge, England) - 1 Jan 2009

Suyama Ritsuko, Jenny Andreas, Curado Silvia, Pellis-van Berkel Wendy, Ephrussi Anne

Abstract excerpt

During Drosophila oogenesis, Oskar mRNA is transported to the posterior pole of the oocyte, where it is locally translated and induces germ-plasm assembly. Oskar protein recruits all of the components necessary for the establishment of posterior embryonic structures and of the germline. Tight localization of Oskar is essential, as its ectopic expression causes severe patterning defects. Here, we show that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Body Patterning
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Microfilament Proteins

Share to Oocytes

Share to Protein Transport

Share to src Homology Domains

Source

Identifiers

PMID: 19036801
DOI: 10.1242/dev.027698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.PMID 19036801Read ↗

oskar mRNA is localized to the posterior pole of the Drosophila oocyte.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

Multiple RNA regulatory elements mediate distinct steps in localization of oskar mRNA.Semantic proximity Read ↗

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.Semantic proximity Read ↗

Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole.Semantic proximity Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

A late phase of Oskar accumulation is crucial for posterior patterning of the Drosophila embryo, and is blocked by ectopic expression of Bruno.Semantic proximity Read ↗

Orb and a long poly(A) tail are required for efficient oskar translation at the posterior pole of the Drosophila oocyte.Semantic proximity Read ↗

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation.Semantic proximity Read ↗

Slmb antagonises the aPKC/Par-6 complex to control oocyte and epithelial polarity.Semantic proximity Read ↗

poirot, a new regulatory gene of Drosophila oskar acts at the level of the short Oskar protein isoform.Semantic proximity Read ↗

Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.