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Article

A slow acetylator genotype associated with an increased risk of advanced cervical cancer.

Journal of cancer research and clinical oncology - 1 Dec 2002

Costa Sandra, Medeiros Rui, Vasconcelos André, Pinto Daniela, Lopes Carlos

Abstract excerpt

PURPOSE: Human papillomavirus (HPV) is the major etiological agent associated with cervical cancer. However, other risk factors have been indicated, including carcinogen exposure, oral contraceptive usage, certain nutritional deficiencies, and genetic factors. N-acetyltransferase 2 (NAT2) has an important role in the metabolism of several carcinogens. NAT2 polymorphism modulates the activity of the enzyme, by...

Read the complete abstract on PubMed

Topics

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Share to Acetylation
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genetic Predisposition to Disease

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 12474054
DOI: 10.1007/s00432-002-0391-9

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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