Article
[Relationship between polymorphism of N-acetyltransferase 2 and genetic susceptibility to laryngeal carcinoma].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Mar 2002
Lei Dapeng, Pan Xinliang, Guo Chenhong, Xu Fenglei, Zhang Liqiang, Liu Dayu, Luan Xinyong
Abstract excerpt
OBJECTIVE: To investigate the relationship between polymorphism of N-acetyltransferase (NAT2) gene and genetic susceptibility to laryngeal carcinoma. METHODS: A case-control study on 62 laryngeal carcinoma patients and 56 controls was conducted. NAT2 alleles were differentiated by polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) methods using originally created PCR primers and...
Topics
- Aged
- Alleles
- Arylamine N-Acetyltransferase
- DNA, Neoplasm
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Laryngeal Neoplasms
- Male
- Middle Aged
- Polymorphism, Genetic
- Smoking
- Statistics as Topic
